[abstract] ABILITY OF THE CONTINUCATH 1000 INTRAVASCULAR PaO2 SENSOR TO MEASURE IN VITRO HYPERBARIC OXYGEN TENSION IN SALINE.

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[abstract] ABILITY OF THE CONTINUCATH 1000 INTRAVASCULAR PaO2 SENSOR TO MEASURE IN VITRO HYPERBARIC OXYGEN TENSION IN SALINE.

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Title: [abstract] ABILITY OF THE CONTINUCATH 1000 INTRAVASCULAR PaO2 SENSOR TO MEASURE IN VITRO HYPERBARIC OXYGEN TENSION IN SALINE.
Author: Howe, S; Weaver, LK
Abstract: Measurement of arterial oxygen tension (Pa02) in patients within the hyperbaric environment may provide useful information about the state of oxygenation and the dose of hyperbaric oxygen (HB02). Currently, the only method of measurement requires blood gas analyzers situated within a multiplace chamber and when using the monoplace chamber, by extracting a blood gas sample and analyzing it external to the chamber. With the development of the intravascular Pa02 sensor, the ability to measure oxygenation in a real time and continuous fashion can be accomplished. While primarily intended for use in the operating room and intensive care units, we saw the potential for use in the hyperbaric environment. Because the Intracath Oxygen Monitoring System (Shiley Biomedical Sensors Inc, Kansas City, MO) used with the Continucath 1000 sensor will not function beyond 1 ATA, we constructed an operational amplifier to convert the output of the sensor directly to a voltage. Using this amplifier we measured the output voltage of two sensors (one new and one previously used) immersed in saline in a tonometer (Instrument Laboratories, IL 237, Lexington, MA) over a range of chamber pressures (0.85 -3.0 ATA) with varying concentrations of oxygen (21,60, and 100%; the predicted p02 at 3.0 ATA and 100% oxygen is 2233 mmHg) at physiologic temperatures. Both sensors provided linear voltage responses as a function of p02 from 0.85 ATA to 3.0 ATA [probeA: Pa02 = -0.00114* voltage output -0.20369 (r2 = 0.854075); probe B: Pa02 = -0.00146 * voltage output -0.13566 (r2 = 0.881717)l. While it must be noted that probe A is older than probe B and that aging of the sensor may cause a change in calibration, the response of both are surprisingly linear and sufficient to predict the Pa02 at pressures to 3.0 ATA and 100% oxygen using one point calibration with saline analysis. This preliminary data lead to the interpretation that the Continucath 1000 sensor may be an appropriate tool to inspect the PaO2 or, possibly, the tissue gas tension of HBO2 treated patients. The manufacturer may even wish to consider the construction of a monitor that will function within the hyperbaric range.
Description: Abstract of the Undersea and Hyperbaric Medical Society Annual Scientific Meeting held June 19-23, 1991 at San Diego Princess Resort, San Diego, CA.
URI: http://archive.rubicon-foundation.org/7590
Date: 1991

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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