[abstract] EFFECT OF OZONE ON THE PHAGOCYTOSIS OF ALVEOLAR MACROPHAGES AT 3.1 MPa AND 40 kPa OXYGEN.

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[abstract] EFFECT OF OZONE ON THE PHAGOCYTOSIS OF ALVEOLAR MACROPHAGES AT 3.1 MPa AND 40 kPa OXYGEN.

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Title: [abstract] EFFECT OF OZONE ON THE PHAGOCYTOSIS OF ALVEOLAR MACROPHAGES AT 3.1 MPa AND 40 kPa OXYGEN.
Author: Jakobsen, K; Hag, R; Lindrup, AG; Kambestad, BK
Abstract: Ozone, which is a strong irritant to the mucous membranes and the lungs, is produced in significant amounts during hyperbaric inert gas welding. It is known that ozone reduces the phagocytotic activity of alveolar macrophages, depending on the ozone concentration and duration of exposure. In our experiment we have studied the phagocytosis of rat alveolar macrophages after in vivo exposure to 0.16 Pa (± 0.03 Pal ozone for 10 minutes, both at 3.1 MPa and 0.2 MPa total pressure (40 kPa oxygen). The phagocytotic capacity of alveolar macrophages was not significantly changed by ozone exposure at 0.2 MPa. However, at 3.1 MPa the macrophages' phagocytosis was significantly decreased after ozone exposure. The phagocytosis was also studied after exposure to pressure alone (3.1 MPa), but, no effect of pressure alone could be observed on the phagocytotic activity of the alveolar macrophages. These experiments indicate that an increase in total pressure may increase the ozone toxicity on phagocytosis of alveolar macrophages.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Joint Annual Scientific Meeting with the International Congress for Hyperbaric Medicine and the European Undersea Biomedical Society held 11-18 August 1990. Okura Hotel, Amsterdam, The Netherlands (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/7220
Date: 1990

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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