[abstract] (18)FDG POSITRON EMISSION TOMOGRAPHY (PET) AND PROGNOSIS IN LOWER LIMB WOUNDS.

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[abstract] (18)FDG POSITRON EMISSION TOMOGRAPHY (PET) AND PROGNOSIS IN LOWER LIMB WOUNDS.

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dc.contributor.author Buesser, PJ
dc.contributor.author Moon, RE
dc.contributor.author Hoffman, JM
dc.contributor.author Coleman, RE
dc.contributor.author Hanson, M
dc.contributor.author McCann, RL
dc.date.accessioned 2008-06-27T13:46:42Z
dc.date.available 2008-06-27T13:46:42Z
dc.date.issued 1992
dc.identifier.uri http://archive.rubicon-foundation.org/7202
dc.description Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held June 23-27, 1992. Hyatt Regency Bethesda Hotel, Bethesda, Maryland (http://www.uhms.org) en
dc.description.abstract Seven patients with non-healing, ischemic lower extremity wounds without osteomyelitis were evaluated with PET using (18)F-deoxyglucose (FDG). Revascularization was deemed impossible in all patients. Scans were obtained simultaneously of both legs. An average of 7 images (range 3 to 9) were obtained on each patient after injection of an average of 10.1 millicuries (mCi) of FDG using a ECAT III scanner (CTI, Knoxville, TN). Following the PET study 5 of 7 patients underwent hyperbaric oxygen (HBO) therapy at 2 ATA for 2 hours. The average number of HBO treatments was 25.6 (range 12 to 54). Of the patients treated with HBO one died of other causes within a month, three required BKA, one underwent skin grafting and healed successfully after a second course of HBO. The two patients who did not receive HBO healed eventually with successful skin grafts. Increased FDG uptake was consistently noted in the affected limb, presumably indicating hypermetabolism. There were no obvious differences between healers and non-healers in the pattern of FDG uptake. One patient had increased uptake in the contralateral limb and eventually required amputation on that side. This preliminary study suggests that metabolism in areas adjacent to non-healing wounds is higher than in normal tissue, despite clinical evidence of ischemia. Evidence of increased FDG uptake is not necessarily a sign of viable tissue. en
dc.format.extent 258 bytes
dc.format.mimetype text/plain
dc.language.iso en en
dc.publisher Undersea and Hyperbaric Medical Society, Inc. en
dc.subject POSITRON EMISSION TOMOGRAPHY en
dc.subject PET en
dc.subject hyperbaric oxygenation en
dc.subject HBO en
dc.subject FDG en
dc.subject F-deoxyglucose en
dc.subject non-healing en
dc.subject ischemia en
dc.subject leg en
dc.subject lower extremity en
dc.subject metabolism en
dc.title [abstract] (18)FDG POSITRON EMISSION TOMOGRAPHY (PET) AND PROGNOSIS IN LOWER LIMB WOUNDS. en
dc.type Other en

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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