[abstract] MODELING, MEASUREMENTS, AND MOMENTS OF INERT GAS EXCHANGE.

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[abstract] MODELING, MEASUREMENTS, AND MOMENTS OF INERT GAS EXCHANGE.

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Title: [abstract] MODELING, MEASUREMENTS, AND MOMENTS OF INERT GAS EXCHANGE.
Author: Weathersby, PK; Homer, LD
Abstract: Measurements of xenon gas exchange over 7 h in anesthetized dogs were fitted to a number of mechanistic models of capillary gas exchange. Both simple blood perfusion and simple tissue diffusion models failed to adequately fit the data. Models that combined blood perfusion with either radial or axial diffusion in the capillary fit the data, but only with implausible values of physiologic variables. Thus, it was concluded that some form of capillary heterogeneity must be formally included in reasonable models of tissue gas exchange. The models used could be summarized by the moments (e. g. mean and standard deviation) of the distribution of gas-molecule transit times in the capillary. These moments provided a very useful framework for model comparison and development because models that fitted data well gave similar estimates of moments, regardless of which physical mechanisms of gas transport were assumed. Poorly fitting models gave different values of moments. Numerical values and properties of the moments establish constraints for any generally useful model. (UHMS SPON: J. Vorosmarti)
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. The 7th Symposium on Underwater Physiology Meeting with the European Undersea Biomedical Society held 5-10 July 1980. The Athens Hilton Hotel, Athens, Greece (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/6835
Date: 1980

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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