[abstract] HBO AS ADJUNCTIVE THERAPY FOR WOUND HEALING COMPLICATIONS IN IRRADIATED TISSUES OUT OF THE HEAD AND NECK.

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[abstract] HBO AS ADJUNCTIVE THERAPY FOR WOUND HEALING COMPLICATIONS IN IRRADIATED TISSUES OUT OF THE HEAD AND NECK.

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Title: [abstract] HBO AS ADJUNCTIVE THERAPY FOR WOUND HEALING COMPLICATIONS IN IRRADIATED TISSUES OUT OF THE HEAD AND NECK.
Author: Matos, LA; Lopez, EA; Shellenberger, TD
Abstract: BACKGROUND: Use of ionizing radiation for treatment of malignancies in areas others than the Head and Neck is a routine modality of therapy either as primary treatment or in combination with surgery and/ or chemotherapy. Reports of the occurrence of complications related to radiotherapy and the use of HBO in these patients are limited. If this is consequence of a different biologic behavior of the malignancies occurring in these regions (i.e. decreased recurrences, responses to lesser radiation dosages) or their anatomic composition remains to be proven. We describe our experience with the use of HBO therapy in the management of wound healing complications related to radiation soft tissue injury. METHODS: A retrospective chart review of 24 consecutive patients over a seven year period (1992 to 1998) referred for HBO therapy after developing wound healing complications related to irradiation exposure of the affected areas. Cases were included only if adequate information was present regarding anatomic location of the wound and its description, radiation dosages, corresponding number of HBO sessions, and status of wound at the end of therapy. Successful outcome was considered only if resolution of infection, formation of a clean and healthy granulation bed that progressed to heal spontaneously or in preparation for reconstructive surgery, was obtained. The opposite was criteria for failure. HBO therapy was delivered in a multiplace chamber at 2.4 ATA x 90 minutes on a daily basis. RESULTS: The abdomen, pelvis and perineum were in conjunction the most affected regions (54%), followed by the extremities (29%), and the torso (17%). Wounds were characterized mostly by moderate sized soft tissue defects that could encompass full thickness of skin, subcutaneous and underlying soft tissues (fascia and muscle), presence of necrotic and/or fibrinous tissues, lack of granulation, and surrounding dense fibrosis. 62.5% of the cases received radiation dosages over 5000 cGy. A successful criterion was achieved in 84% of the cases. In this group the average number of HBO treatments was 30.2. CONCLUSIONS: In areas of the body others than the Head and Neck with refractory wounds and previous irradiation, HBO therapy can accomplish successful resolution in the majority of the cases.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/6642
Date: 2000

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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