[abstract] 18F-DEXOYGLUCOSE POSITRON EMISSION TOMOGRAPHY (PET) IN THE EVALUATION OF NEUROLOGICAL DECOMPRESSION ILLNESS

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[abstract] 18F-DEXOYGLUCOSE POSITRON EMISSION TOMOGRAPHY (PET) IN THE EVALUATION OF NEUROLOGICAL DECOMPRESSION ILLNESS

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dc.contributor.author Moon, RE
dc.contributor.author Hoffman, JM
dc.contributor.author Hanson, MW
dc.contributor.author Reiman, RE
dc.contributor.author Coleman, RE
dc.contributor.author Theil, DR
dc.contributor.author Fawcett, TA
dc.contributor.author Fracica, PJ
dc.contributor.author Gorback, MS
dc.contributor.author Massey, EW
dc.date.accessioned 2008-04-25T02:55:13Z
dc.date.available 2008-04-25T02:55:13Z
dc.date.issued 1991
dc.identifier.citation Abstract of the Undersea and Hyperbaric Medical Society Annual Scientific Meeting held June 19-23, 1991 at San Diego Princess Resort, San Diego, CA en
dc.identifier.uri http://archive.rubicon-foundation.org/6477
dc.description.abstract Advanced imaging techniques may demonstrate structural (CT, MRI), perfusion (Xe-enhanced CT, SPECT [single photon emission computed tomography]) or metabolic abnormalities (PET) in patients with decompression illness (DCI). Studies using SPECT have suggested cerebral perfusion abnormalities in divers with pure spinal cord DCI. PET has a higher resolution than SPECT and is more likely to reflect abnormal cellular function. Using PET, we looked for areas of cerebral hypometabolism in divers with neurological DCI. 17 divers (11 male, 6 female) (ages 21 -46 years; mean 33.8) were evaluated. 5 patients had predominantly cortical symptoms, 7 had predominantly spinal cord symptoms, and 5 had mixed symptomatology. Median delay between accident and scan was 11 weeks (range 5 days to 340 weeks). 9/17 divers had abnormal neurological exams at the time of the scan. Scans were obtained in supine position after injection of 10 mC of 18F-DG. Using a CTI instrument, with 8.6 mm in-plane resolution, 15 image planes were obtained covering the entire intracranial contents, with 8 mm plane thickness. Scans were graded independently by two radiologists on the following scale: I-definitely normal, II-probably normal, III-equivocal, IV-probably abnormal, V-definitely abnormal. The majority (14/17) of the scans were graded normal or probably normal. TABLE: Grade, I, II, III, IV, V; Cortical abnormalities, 5, 2, 1, 1, 1; Spinal cord abnormalities only, 2, 5, 0, 0, 0; Total, 7, 7, 1, 1, 1; . A grade V scan was obtained 5 days after an accident in a diver who had profound dysphasia and hemiparesis. Another diver who complained of memory lapses and disequilibrium after an arterial gas embolism had a grade IV scan 11 weeks after the incident. We conclude that in the absence of neurological signs or symptoms, there is no significant evidence of regional cerebral hypometabolism in patients with DCI. Physical exam remains the primary diagnostic tool in identifying neurologic decompression illness. en
dc.format.extent 193 bytes
dc.format.mimetype text/plain
dc.language.iso en_US en
dc.publisher Undersea and Hyperbaric Medical Society, Inc. en
dc.subject (18)F-deoxyglucose en
dc.subject PET en
dc.subject neurological DCI en
dc.subject decompression illness en
dc.subject DCS en
dc.subject decompression sickness en
dc.subject human en
dc.subject cerebral hypometabolism en
dc.subject brain scan en
dc.title [abstract] 18F-DEXOYGLUCOSE POSITRON EMISSION TOMOGRAPHY (PET) IN THE EVALUATION OF NEUROLOGICAL DECOMPRESSION ILLNESS en
dc.type Other en

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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