[abstract] CHANGES IN BONE MARROW CIRCULATION FOLLOWING SIMULATED DIVES, AS INDICATED BY INTRAOSSEOUS PHLEBOGRAPHY

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[abstract] CHANGES IN BONE MARROW CIRCULATION FOLLOWING SIMULATED DIVES, AS INDICATED BY INTRAOSSEOUS PHLEBOGRAPHY

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Title: [abstract] CHANGES IN BONE MARROW CIRCULATION FOLLOWING SIMULATED DIVES, AS INDICATED BY INTRAOSSEOUS PHLEBOGRAPHY
Author: Pooley, J; Walder, DN
Abstract: Previously we reported that a reduction in blood flow, indicated by a Xenon depot clearance technique occurs in rabbit femoral bone marrow during and for some time following simulated air dives to 2Om. The effect of saturation exposures to compressed-air on bone marrow circulation has been further investigated by the method of intraosseous phlebography. The clearance of a depot of radiopaque contrast medium intrcduced into the marrow of the rabbit distal femur has been monitored by serial radiography, before and after simulated air dives to 20 m for 4 hours. It was confirmed in control animals that a bolus of radiopaque contrast medium rapidly outlines the intramedullary central venous sinus and is present in extra-osseous veins within 1 sec of injection. Following a simulated air dive to 20 m for 4 hours injected contrast medium remains as a pool in the marrow tissue for periods of 15 sec or longer, extra-osseous veins are poorly outlined and subtraction films demonstrate that the central medullary venous sinus, when visible, is markedly attenuated. When a period of 1.5 hours had elapsed after the dives the phlebographic appearances were found to have reverted to the pre-dive control pattern. This evidence supports that of the isotope clearance studies in indicating that a saturation exposure to compressed-air results in a reduction in blood flow in rabbit femoral bone marrow. We have found evidence of an increase in fat cell volume following exposure to compressed-air in vitro and postulated that should this occur in the marrow cavity in vivo it would account for the observed decrease in tissue perfusion. The phlebographic appearances following exposure to compressed-air are consistent with this hypothesis.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 25-29, 1981. The Asilomar Conference Center, Pacific Grove, California (http:www.uhms.org)
URI: http://archive.rubicon-foundation.org/4883
Date: 1981

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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