[abstract] QUANTITATIVE COMPARISON BY REGION OF INERT GAS EXCHANGE IN DOGS.

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[abstract] QUANTITATIVE COMPARISON BY REGION OF INERT GAS EXCHANGE IN DOGS.

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Title: [abstract] QUANTITATIVE COMPARISON BY REGION OF INERT GAS EXCHANGE IN DOGS.
Author: Weathersby, PK; Mendenhall, KG; Barnard, EEP; Homer, LP; Fraser, LM; Suryawanshi, S; Vieras, F
Abstract: Decompression theories generally presume the existence of a number of anatomic organs or mathematical "tissue compartments" with widely varying gas exchange characteristics. In order to obtain quantitative information regarding the distribution of gas quantity and exchange rates in an animal we allowed anesthetized dogs to breath small amounts of Xenon-133 for periods of 10 to 50 minutes and then room air for a subsequent six hours. During the entire period the xenon gas concentrations in large regions of the animal were measured with a gamma camera that allowed resolution of several thousand locations with dimensions on the order of 1 cm. Exponential xenon analysis with various "half-times" did not allow useful comparisons among data sets. Instead, the results are presented in terms of moments of the residence time distribution function of each location in the dog. We have obtained maps of the mean residence time (i.e. the first moment) that indicate large variations in both gas quantity and gas exchange rates within a dog. For example, in locations near the heart and in the center of the brain mean residence times are 5 to 10 minutes; shaft regions of long bones have mean times about 30 minutes; and some joint areas have mean residence times over 100 minutes.
URI: http://archive.rubicon-foundation.org/4604
Date: 1979

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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