[abstract] RADICAL VULVECTOMY IN VULVAR CARCINOMA - HBO PREVENTION AND TREATMENT OF SURGICAL DEHISCENCES

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[abstract] RADICAL VULVECTOMY IN VULVAR CARCINOMA - HBO PREVENTION AND TREATMENT OF SURGICAL DEHISCENCES

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Title: [abstract] RADICAL VULVECTOMY IN VULVAR CARCINOMA - HBO PREVENTION AND TREATMENT OF SURGICAL DEHISCENCES
Author: Iazzetti, PE; Verdiani, LA; Panetta, K; Derchain, SFM
Abstract: BACKGROUND: Vulvar neoplasies constitute 3-5percent of female genital cancers. The women population that went to our medical center with such neoplasies have more than fifty years and the majority had epidermoid carcinoma in advanced states, which responds poorly to chemoradiotherapy, indicating broad surgical debridement. Almost all the cases of radical vulvectomy had complicated surgical dehiscences in the groin area and common associated post-operatory problems were age, poor nutrition, diabetes and arterial hypertension. METHODS: Vulvar carcinoma patients, with vulvectomy and inguinocrural lymphadenectomy, with primary closure of surgical wound, included 28 consecutive women. Twenty-one were treated in conventional way (average 66.6 years) and the last 7 patients were treated with HBO (average 62.4 years), with one daily session (2 ATA, 90 minutes) for 7 - 15 days (average 12 days), beginning 24 hours after surgery. All the patients were in stage II and III (FIGO), except one, in HBO group that was in stage IV. The surgical procedure and other conventional therapeutic measures (antibiotics, fluid reposition, continuous wound drainage, local dressings, etc.) were the same for both groups. RESULTS: The hospital average stay was 17.5 days for HBO group versus 20 days in control group. The immediate post-operatory complications (like fever, purulent drainage and cellulitis) were clearly reduced in the HBO group, and the hospital stay was extended only to conclude HBO sessions. In the control group 95percent cases had total dehiscence of surgical wound early (2-3 days). In the HBO group occurred 86percent of partial dehiscences, but more later (5-7 days), increasing the conditions to granulation tissue formation and allowing second intention healing. CONCLUSIONS: Although it was a limited group in this preliminary study, HBO showed evident beneficial results. Reinforcing the role of HBO as a useful complementary therapy in surgical dehiscences in selected cases, especially if started early, in the immediate post-operatory period.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: http://archive.rubicon-foundation.org/434
Date: 1997

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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