[abstract] RADIATION LATE EFFECTS CLINIC - A GOOD IDEA? THE ROLE OF AN HBO PHYSICIAN IN THE TEAM

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[abstract] RADIATION LATE EFFECTS CLINIC - A GOOD IDEA? THE ROLE OF AN HBO PHYSICIAN IN THE TEAM

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Title: [abstract] RADIATION LATE EFFECTS CLINIC - A GOOD IDEA? THE ROLE OF AN HBO PHYSICIAN IN THE TEAM
Author: Evans, AW; Austen, L; Levin, W
Abstract: INTRODUCTION: A small proportion of patients treated with radiotherapy to cure cancer will suffer permanent radiation late effects (RLE) on the normal tissues. Due to the physico-chemical reactions set up in all tissues by the irradiation, a degree of collateral damage to nearby non-malignant tissue is inevitable. Until recently there has been little to offer to those who have developed "collateral damage" morbidity other than symptomatic management. With better understanding of the relevant pathophysiology, interventions have been developed to modify the natural history of post radiotherapy changes most notably soft tissue necrosis, pain, and fibrosis. RLE manifests differently in various organ systems. Treatment options include HBO and various pharmacological agents including antioxidants and vasoactive drugs. METHODOLOGY: In 2000 an adult late radiation effects clinic was established in our hospital to collect patient data, to manage these patients and keep records of the outcome of treatments. The clinic is unique in our experience. We continue to develop and improve protocols for data collection and treatment to facilitate prospective research. RESULTS: More than 100 patients have been seen in the clinic. Princess Margaret Hospital - Radiation Late Effects Clinic As of Jan.1, 2003, Total database patients Site, anal 4, breast 26, HN 24, cervix 15, Endometrium 5, Ovary 1, extremity 5, lung 1, lymphoma 1, skin 1, penis 2, prostate 6, UKP 3, vagina/vulva 4, Total 98. CONCLUSIONS: The functional impairments under are often multifactorial. There is a need for comprehensive baseline documentation using validated measurements to ensure study integrity. Determination of which parameters are relevant is still uncertain. Ensuring reproducibility of serial clinical measurements is a challenge. An attempt to standardize such information collection is being undertaken. DISCUSSION: Recommended data collection parameters/content will be presented for debate.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: http://archive.rubicon-foundation.org/1365
Date: 2003

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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