[abstract] N-TERMINAL PRO-B-TYPE NATRIURETIC PEPTIDE INCREASES AFTER HYPERBARIC OXYGEN THERAPY IN DIABETIC PATIENTS.

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[abstract] N-TERMINAL PRO-B-TYPE NATRIURETIC PEPTIDE INCREASES AFTER HYPERBARIC OXYGEN THERAPY IN DIABETIC PATIENTS.

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Title: [abstract] N-TERMINAL PRO-B-TYPE NATRIURETIC PEPTIDE INCREASES AFTER HYPERBARIC OXYGEN THERAPY IN DIABETIC PATIENTS.
Author: Uzun, G; Yildiz, S; Uz, O; Ipcioglu, OM; Kardesoglu, E; Ozcan, O
Abstract: INTRODUCTION: Diabetic patients receive hyperbaric oxygen (HBO) therapy for non-healing lower extremity ulcers. Exposure to HBO may affect cardiovascular functions by different mechanisms. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a cardiac neurohormone. The main stimulus for synthesis and secretion of NTproBNP is myocardial wall stress as a result of ventricular volume expansion and pressure overload. The aim of this study was to investigate the effect of HBO therapy on NT-proBNP levels in diabetic patients. MATERIALS AND METHODS: Twenty-five diabetic patients (19 male and 6 female, 64.7 ± 10.2 yr), who were planning to undergo HBO therapy, were consecutively enrolled. All patients were evaluated with echocardiography before the study. Venous blood samples were drawn from each patient before and after the HBO therapy for NTproBNP analysis. RESULTS: Heart rate and arterial blood pressure of patients did not change significantly with HBO therapy (p>0.05). However, NT-proBNP levels increased significantly after HBO therapy compared to the pretreatment values (p<0.05). CONCLUSIONS: HBO therapy induces significant ventricular wall stress in diabetic patients and care should be taken when a diabetic patient with cardiovascular disease is treated with HBO therapy.
Description: Abstract of the Undersea & Hyperbaric Medical Society 2008 Annual Scientific Meeting June 26-28, 2008 Salt Lake City Marriott Downtown, Salt Lake City, Utah.
URI: http://archive.rubicon-foundation.org/7871
Date: 2008

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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