[abstract] INCIDENCE OF VITAMIN D DEFICIENCY IN PATIENTS EVALUATED FOR HYPERBARIC OXYGEN THERAPY FOR WOUNDS, INFECTION, OR RADIATION INJURY.

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[abstract] INCIDENCE OF VITAMIN D DEFICIENCY IN PATIENTS EVALUATED FOR HYPERBARIC OXYGEN THERAPY FOR WOUNDS, INFECTION, OR RADIATION INJURY.

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dc.contributor.author Holm, JR
dc.contributor.author Weaver, LK
dc.contributor.author Carlson, R
dc.contributor.author Churchill, SK
dc.contributor.author Wilson, GR
dc.contributor.author Lloyd, CA
dc.contributor.author Wegesser, WB
dc.date.accessioned 2008-11-04T21:54:31Z
dc.date.available 2008-11-04T21:54:31Z
dc.date.issued 2008
dc.identifier.citation Undersea Hyperb Med. 2008 July-Aug;35(4) en
dc.identifier.issn 1066-2936
dc.identifier.uri http://archive.rubicon-foundation.org/7856
dc.description Abstract of the Undersea & Hyperbaric Medical Society 2008 Annual Scientific Meeting June 26-28, 2008 Salt Lake City Marriott Downtown, Salt Lake City, Utah. en
dc.description.abstract INTRODUCTION: Severe vitamin D deficiency has been associated with rickets. Recent studies report that vitamin D can decrease the risk of many chronic illnesses, including cancers and autoimmune, infectious, and cardiovascular diseases.1 Since many patients receiving hyperbaric oxygen therapy have underlying chronic illness or infection, we were interested the incidence of Vitamin D deficiency in these patients. METHODS: From 8/15/2007 to 3/14/2008, 30 patients were referred for hyperbaric oxygen therapy for complicated wounds, infection, or radiation injury. One patient was excluded due to concurrent vitamin D supplementation (1300 IU vitamin D3 for 5 months). The 29 remaining patients had serum vitamin D 25-hydroxy levels performed by ARUP Laboratories (Salt Lake City, Utah). Laboratory reference values defined vitamin D deficiency as <20 ng/mL, insufficiency 20-29 ng/mL, optimal 30-80 ng/mL and possibly toxic >80 ng/mL. All patients were given supplemental vitamin D if they had deficient or insufficient levels. RESULTS: Of 29 tested patients, 21 were male, 8 female. Twenty-four were Caucasian, 4 Hispanic, and 1 Asian. Indications for hyperbaric oxygen therapy were compromised flap (10), bony/soft tissue radiation injury (8), chronic refractory osteomyelitis (7), or progressive necrotizing soft tissue infection (4). Mean vitamin D 25-hydroxy levels were 21±15 ng/mL (range <7-69 ng/mL). Nineteen patients (66%) had deficiency, 3 (10%) had insufficiency, 7 (24%) had optimum levels, and none had possible toxicity. CONCLUSIONS: In patients evaluated for hyperbaric oxygen therapy for wounds, infection, or radiation injury, vitamin D insufficiency or deficiency is common (76%). Since vitamin D is essential for fighting infection, wound healing, and other parameters of health, we recommend obtaining a vitamin D 25-hydroxy serum level on these patients and initiating supplemental replacement if needed. Further studies are needed to determine whether vitamin D testing and supplementation impact clinical outcomes. 1 Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81. en
dc.format.extent 193 bytes
dc.format.mimetype text/plain
dc.language.iso en en
dc.publisher Undersea and Hyperbaric Medical Society, Inc. en
dc.subject supplementation en
dc.subject VITAMIN D DEFICIENCY en
dc.subject wound en
dc.subject infection en
dc.subject RADIATION INJURY en
dc.subject clinical outcome en
dc.subject HUMANS en
dc.title [abstract] INCIDENCE OF VITAMIN D DEFICIENCY IN PATIENTS EVALUATED FOR HYPERBARIC OXYGEN THERAPY FOR WOUNDS, INFECTION, OR RADIATION INJURY. en
dc.type Article en

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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