[abstract] INCIDENCE OF VITAMIN D DEFICIENCY IN PATIENTS EVALUATED FOR HYPERBARIC OXYGEN THERAPY FOR WOUNDS, INFECTION, OR RADIATION INJURY.

Rubicon Research Repository/Manakin Repository

[abstract] INCIDENCE OF VITAMIN D DEFICIENCY IN PATIENTS EVALUATED FOR HYPERBARIC OXYGEN THERAPY FOR WOUNDS, INFECTION, OR RADIATION INJURY.

Show full item record


Title: [abstract] INCIDENCE OF VITAMIN D DEFICIENCY IN PATIENTS EVALUATED FOR HYPERBARIC OXYGEN THERAPY FOR WOUNDS, INFECTION, OR RADIATION INJURY.
Author: Holm, JR; Weaver, LK; Carlson, R; Churchill, SK; Wilson, GR; Lloyd, CA; Wegesser, WB
Abstract: INTRODUCTION: Severe vitamin D deficiency has been associated with rickets. Recent studies report that vitamin D can decrease the risk of many chronic illnesses, including cancers and autoimmune, infectious, and cardiovascular diseases.1 Since many patients receiving hyperbaric oxygen therapy have underlying chronic illness or infection, we were interested the incidence of Vitamin D deficiency in these patients. METHODS: From 8/15/2007 to 3/14/2008, 30 patients were referred for hyperbaric oxygen therapy for complicated wounds, infection, or radiation injury. One patient was excluded due to concurrent vitamin D supplementation (1300 IU vitamin D3 for 5 months). The 29 remaining patients had serum vitamin D 25-hydroxy levels performed by ARUP Laboratories (Salt Lake City, Utah). Laboratory reference values defined vitamin D deficiency as <20 ng/mL, insufficiency 20-29 ng/mL, optimal 30-80 ng/mL and possibly toxic >80 ng/mL. All patients were given supplemental vitamin D if they had deficient or insufficient levels. RESULTS: Of 29 tested patients, 21 were male, 8 female. Twenty-four were Caucasian, 4 Hispanic, and 1 Asian. Indications for hyperbaric oxygen therapy were compromised flap (10), bony/soft tissue radiation injury (8), chronic refractory osteomyelitis (7), or progressive necrotizing soft tissue infection (4). Mean vitamin D 25-hydroxy levels were 21±15 ng/mL (range <7-69 ng/mL). Nineteen patients (66%) had deficiency, 3 (10%) had insufficiency, 7 (24%) had optimum levels, and none had possible toxicity. CONCLUSIONS: In patients evaluated for hyperbaric oxygen therapy for wounds, infection, or radiation injury, vitamin D insufficiency or deficiency is common (76%). Since vitamin D is essential for fighting infection, wound healing, and other parameters of health, we recommend obtaining a vitamin D 25-hydroxy serum level on these patients and initiating supplemental replacement if needed. Further studies are needed to determine whether vitamin D testing and supplementation impact clinical outcomes. 1 Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81.
Description: Abstract of the Undersea & Hyperbaric Medical Society 2008 Annual Scientific Meeting June 26-28, 2008 Salt Lake City Marriott Downtown, Salt Lake City, Utah.
URI: http://archive.rubicon-foundation.org/7856
Date: 2008

Files in this item

Files Size Format View
abstract.txt 193bytes Text file View/Open

This item appears in the following Collection(s)

  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

Show full item record

Browse

My Account