[abstract] PARAMETERS ASSOCIATED WITH LATE DETERIORATION IN A CANINE MODEL OF CEREBRAL ARTERIAL GAS EMBOLISM.

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[abstract] PARAMETERS ASSOCIATED WITH LATE DETERIORATION IN A CANINE MODEL OF CEREBRAL ARTERIAL GAS EMBOLISM.

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Title: [abstract] PARAMETERS ASSOCIATED WITH LATE DETERIORATION IN A CANINE MODEL OF CEREBRAL ARTERIAL GAS EMBOLISM.
Author: Dutka, AJ; Pettrone, K; Mink, RB
Abstract: We have previously reported that somatosensory evoked potential (SSEP) amplitude declines during the course of hyperbaric treatment following injection of 0.4 mls of air into the internal carotid if the injection of air is followed shortly by transient severe arterial hypertension. We collected data from 32 pentobarbital anesthetized dogs that have been subjected to this insult and treatment with a modified USN Table 6A as controls for tests of a variety of adjuvant drug treatments. We correlated the amplitude of SSEP 2 min after air injection, maximum mean blood pressure, duration of hypertensive response, and the interval between air injection and injection of norepinephrine to produce hypertension (the norepinephrine injection is coincident with leaving the surface for treatment) with the final percent recovery of baseline SSEP amplitude, using a multiple regression. The final recovery (28.7% +- 15.4% mean +- SD) is significantly related only to the interval between air injection and injection of norepinephrine (7.0 +- 1.9 min). This result suggests that outcome is not related to the severity of the insult but is related to delay either in treatment or exposure of arteries damaged by gas to further damage by arterial hypertension. (Supported by NMRDC Work Unit No. MRO4101.001-1005).
Description: Abstract of the Undersea and Hyperbaric Medical Society Annual Scientific Meeting held June 19-23, 1991 at San Diego Princess Resort, San Diego, CA.
URI: http://archive.rubicon-foundation.org/7422
Date: 1991

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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