[abstract] IMPACT OF HYPERBARIC OXYGEN ON RADIATION INDUCED XEROSTOMIA IN PATIENTS WITH MALIGNANCIES OF THE HEAD AND NECK.

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[abstract] IMPACT OF HYPERBARIC OXYGEN ON RADIATION INDUCED XEROSTOMIA IN PATIENTS WITH MALIGNANCIES OF THE HEAD AND NECK.

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Title: [abstract] IMPACT OF HYPERBARIC OXYGEN ON RADIATION INDUCED XEROSTOMIA IN PATIENTS WITH MALIGNANCIES OF THE HEAD AND NECK.
Author: Fontanesi, J; Beckford, N; Golden Jr, EB; Cianci, P
Abstract: Approximately 8000 patients will be diagnosed with malignancy in the head and neck region in the United States in 1990. Modern therapy often utilizes cytoeductive chemotherapy, surgical extirpation and irradiation. The utilization of hyperbaric oxygen (HBO) has most recently been confined to treatment of soft tissue radionecrosis (STR). Although not known, it is suspected that the incidence of STR has been increasing because of more aggressive combined therapy. It has been noticed in patients undergoing HBO for STR that there has been subjective resolution of xerostomia and its associated complications. We endeavored to assess the effect of HBO on xerostomia in pat ients at least 6 mos post therapy which inc luded irradiation of a minimum 50 6y to both parotid and submandibular glands. 3 patients have completed therapy and are a minimum 6 wks post HBO. Each patient had salva measured by use of a simple measured collection system. Following no oral intake for 12 hours, salva was collected for 30 minutes. This test was repeated every month. Each patient was treated once a day to two atmospheredds for 90 minutes. This was delivered in 20 treatments. Initial pre HBO salivary measurements were 5, 5, and 12 cc's. At completion salivary measurements were 15. 18, and 14 cc' s. At t mos post HBO a 11 reported marked improvement starting approximately 2 weeks earlier. Salivary function at t mos was 45, 60, and 65 cc respectively; although this experience is early and requires maturation it would be reasonable to study the use of HBO for resolution of xerostomia.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Joint Annual Scientific Meeting with the International Congress for Hyperbaric Medicine and the European Undersea Biomedical Society held 11-18 August 1990. Okura Hotel, Amsterdam, The Netherlands (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/7068
Date: 1990

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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