[abstract] OXYGEN TOXICITY PREVENTION IN PATIENTS UNDERGOING HYPERBARIC THERAPY.

Rubicon Research Repository/Manakin Repository

[abstract] OXYGEN TOXICITY PREVENTION IN PATIENTS UNDERGOING HYPERBARIC THERAPY.

Show full item record


Title: [abstract] OXYGEN TOXICITY PREVENTION IN PATIENTS UNDERGOING HYPERBARIC THERAPY.
Author: De Martino, G; Ortolani, O; Santangelo, E; Celano, S; Abate, C
Abstract: The therapeutic effects obtainable with Hyperbaric Therapy (OTI) are often limited by unwanted side effects mediated mainly by Oxygen Free Radicals (FRO). For two years our patients have been receiving FRO scavengers in order to reduce the FRO tissue peroxidative damages limiting the therapeutical index of OTI. Fifty patients who underwent OTI in the last two years for cerebral ischemia, limb gangrene and other pathologies, were divided into two randomized groups. One group received an oral antioxidant mixture ( vit C 50 mg/Kg, Vit E 30 mg/Kg, Alpha-mercaptopropionylglycine 5 mg/kg ) twice a day from the day before OTI was started. The other group received normal therapy. During the OTI ( 2.8 ATA, 60 • 1n air, daily) lipid peroxidation and red cell rigidity were evaluated by laboratory parameters. A marked reduction of some peroxidative alkanes was observed in the expirated air of the threated patients. Red cell filtration was also increased in the untreated group when compared with the ones receiving antioxidants.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Joint Annual Scientific Meeting with the International Congress for Hyperbaric Medicine and the European Undersea Biomedical Society held 11-18 August 1990. Okura Hotel, Amsterdam, The Netherlands (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/6964
Date: 1990

Files in this item

Files Size Format View
abstract.txt 193bytes Text file View/Open

This item appears in the following Collection(s)

  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

Show full item record

Browse

My Account