[abstract] THE TREATMENT OF INTRACTABLE SEIZURES WITH HYPERBARIC 100% OXYGEN.

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[abstract] THE TREATMENT OF INTRACTABLE SEIZURES WITH HYPERBARIC 100% OXYGEN.

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Title: [abstract] THE TREATMENT OF INTRACTABLE SEIZURES WITH HYPERBARIC 100% OXYGEN.
Author: Negron, FL; Jacques, S; Kopyov, O; Laird, C
Abstract: BACKGROUND: Intractable seizures are a difficult medical problem. There is no consensus for the appropriate treatment of patients who have intractable seizures. This is a case presentation of a five year old white male who developed intractable seizures after the removal of an astrocytoma. He experienced 20 seizures per day. Toxic levels of carbamazepine, diphenyl hydantoin, phenobarbital, and valproic acid failed to control the seizures, He developed severe liver toxicity, gastric ulcer and immune suppression, from the antiseizure medication. The control of these seizures would require a great deal of sedation with lorazepam (Ativan) and phenobarbital. His motor and cognitive function would require 24 to 48 hours to return to his base line. In Russia, such intractable seizures have been successfully treated with HBO. It was decided to try the therapy on this patient. METHODS: The patient was placed in an ETC monoplace chamber and the protocol was 2.2 ATA of 100% Oxygen for one hour. He was treated four times per week for five months. RESULTS: The patient's seizures decreased significantly. His medications were reduced from 17 to 7, He was placed on one anticonvulsive drug, carbamazepine. On this therapy regime his seizures have been well controlled. He was treated four times per week for five months. HBO Treatments were suspended for a period of two weeks. Without the HBO therapy his seizure rate increased drastically to approximately 20 per day. CONCLUSION: This patient with intractable seizures responded favorably to hyperbaric oxygen. The seizures were controlled with little or no use of drugs such as lorazepam. His cognitive and motor functions returned to his original base line within 12 hours post treatment. Hyperbaric oxygen had an profound effect in controlling the intractable seizures in this patient. The positive effect of HBO in this case suggests that HBO may be useful in the treatment of intractable seizures. Further investigation into the effects of HBO therapy on neurological disorders is progressing at our clinic.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held June 22-26, 1994. Westin Hotel, Denver, Colorado (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/5640
Date: 1994

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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