[abstract] WEIGHT LOSS ASSOCIATED WITH PROLONGED EXPOSURE OF MICE TO HELIOX PRESSURES - FROM 30-80 ATA.

Rubicon Research Repository/Manakin Repository

[abstract] WEIGHT LOSS ASSOCIATED WITH PROLONGED EXPOSURE OF MICE TO HELIOX PRESSURES - FROM 30-80 ATA.

Show full item record


Title: [abstract] WEIGHT LOSS ASSOCIATED WITH PROLONGED EXPOSURE OF MICE TO HELIOX PRESSURES - FROM 30-80 ATA.
Author: Hinson, WM; Brauer, RW
Abstract: CD-1 mice were maintained for periods up to 12 days in slightly hyperoxic (0.5 ata) heliox at pressures ranging from 30-80 ata. General chamber temperatures were maintained at 34.5 +/- 0.3 C, and a special heated platform permitted the animals to select higher temperatures for part of their sojourn. Marked weight losses were observed. After five days, these were linearly related to pressure ( W(in g)=S.S-0.17P). Weight loss begins soon after compression and increases with the square root of time at pressure (at 80 ata W(in g)=4.1 o t^O.5). Changing from solid mouse pellets to a semi-soft diet had no influence on the rate of weight loss. Observed weight loss at all times was substantially slower than weight loss in fasting controls. Recovery of body weight following decompression began immediately but even after one week at 1 ata the animals had not reached body weights equal to those of controls never exposed to high pressure. Mechanisms possibly giving rise to these effects will be analyzed and the results will be discussed in terms of their bearing on secondary consequences of high pressure effects on the central nervous system and on the question of functional significance of observed temperature preferenda in high pressure atmospheres. The study reported here has been funded by The Office of Naval Research Contract N00014-7S-C-0468.
Description: Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 29-June 2, 1984. The Gunter Hotel, San Antonio, Texas (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/5373
Date: 1984

Files in this item

Files Size Format View
abstract.txt 259bytes Text file View/Open

This item appears in the following Collection(s)

  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

Show full item record

Browse

My Account