[abstract] MAINTENANCE OF RESPIRATORY AND THERMAL HOMEDSTASIS IN FLUOROCARBON LIQUID BREATHING DOGS.

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[abstract] MAINTENANCE OF RESPIRATORY AND THERMAL HOMEDSTASIS IN FLUOROCARBON LIQUID BREATHING DOGS.

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dc.contributor.author Balzer, RE
dc.contributor.author Matthews, JH
dc.contributor.author Kylstra, JA
dc.date.accessioned 2007-12-26T20:53:07Z
dc.date.available 2007-12-26T20:53:07Z
dc.date.issued 1976
dc.identifier.uri http://archive.rubicon-foundation.org/5251
dc.description Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 12-13, 1976. Carillon Hotel, Miami Beach, FL (http:www.uhms.org) en
dc.description.abstract One of the problems in diving physiology is to discriminate between effects of hydrostatic pressure and pharmacologic effects of compressed gases. A definitive answer would require hydraulic compression of liquid breathing animals in which respiratory and thermal homeostasis is maintained, but this has not unequivocally been shown to be possible thus far. We report here on experiments in which 5 pure bred beagle dogs (vTeight = 10.8 + 1.1 kg), anesthetized with sodium pentobarbital and paralyzed with pancuroniurn, were ventilated for 60 minutes with bubble oxygenated FC-80 fluorocarbon (PI02 = 620 ~ 10 ~Ig, PIC02 = 4.5 ~ 0.6 mmHg). Normal body temperature (rectal temperature = 38.1 + O. 2OC) was maintained throughout the experiment. Arterial and mixed venous blood, and inspired, end-tidal and mixed expired liquid 02 and CO2 partial pressures were measured at 10, 20 I 30 I 45 and 60 minutes after the onset of liquid ventilation. A summary of the results is shown below. FC-80 ventilation (min) 10 20 30 45 60; VT (rnl) , 292+3 291+2 290+4 289+3 289+4; f (breq.ths/min) 2.8+0.2 2.7+0.4 2.8+0.3 2.8+0.3 2.8+0.3; \702 (rnl STPD/min) 7l~15 52~12 58+16 54+15 51+16; R .62+.15 .87+.21 .80+.25 .85+.18 .96+.28; PaC02 (mmHg) 42.6+4.4 44.8+3.5 42.4+3.9 40.5+3.3 44.2+3.7; Pa02 (rm1Hg) 316+29 298+22 295+29 315+28 303+21 These results indicate that it is possible to maintain thermal and respiratory homeostasis in anesthetized fluorocarbon liquid breathing dogs. Work supported by Office of Naval Research contract N00014-67-A-025l-0007. en
dc.description.sponsorship US NAVY en
dc.format.extent 259 bytes
dc.format.mimetype text/plain
dc.language.iso en en
dc.publisher Undersea and Hyperbaric Medical Society, Inc. en
dc.subject LIQUID BREATHING en
dc.subject BREATHING GAS en
dc.subject thermal en
dc.subject hydrostatic pressure en
dc.subject Hyperbaric Condition en
dc.subject pharmacologic en
dc.subject respiratory en
dc.subject fluorocarbon en
dc.subject Animal en
dc.subject dog en
dc.title [abstract] MAINTENANCE OF RESPIRATORY AND THERMAL HOMEDSTASIS IN FLUOROCARBON LIQUID BREATHING DOGS. en
dc.type Other en

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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