[abstract] EFFECTS OF HYDROSTATIC PRESSURE ON ARTERIAL PCO2.

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[abstract] EFFECTS OF HYDROSTATIC PRESSURE ON ARTERIAL PCO2.

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dc.contributor.author Kerem, D en_US
dc.contributor.author Salzano, JV en_US
dc.date.accessioned 2006-05-31T03:37:38Z
dc.date.available 2006-05-31T03:37:38Z
dc.date.issued 1974 en_US
dc.identifier.other Undersea Baromedical Research, Vol. 1, No. 1 Appendix, March 1974 en_US
dc.identifier.uri http://archive.rubicon-foundation.org/51
dc.description Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 10-11, 1974. Hilton Hotel, Washington, D.C. (http:www.uhms.org) en_US
dc.description.abstract These experiments were performed to verify observations by Saltzman et al. (J. Appl. Physiol. 30, 443, 1971) on humans exposed to ambient pressures of up to 8.6 Ata, of a positive correlation between Pac02 and ambient pressure and to search for possible mechanisms. In unanesthetized dogs breathing a 3.4% 02 in helium mixture at an ambient pressure of 6.45 Ata (density 1.17 that of air at 1 Ata) for 18 hours, we observed the following changes relative to 1 Ata controls: arterial and cerebrospinal fluid (CSF) Pc02 increased 5 and 4 mm Hg, respectively; CSF (HC03-) increased 2 meq/L; CSF pH was not changed; arterial pH decreased 0.04 units; no change in plasma standard (HC03-). All changes were statistically significant. The magnitude of increase in PaC02 is in agreement with the report of Saltzman et al. and although we are as yet unable to choose between hypoventilation and the increase in CSF bicarbonate as the primary effect of pressure, a very moderate increase in hydrostatic pressure is implicated in affecting respiratory regulation. en_US
dc.description.sponsorship Partially supported by NIH grant HL 13888 en_US
dc.language.iso en_US
dc.rights Abstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 10-11, 1974. Hilton Hotel, Washington, D.C. (http:www.uhms.org) en_US
dc.subject respiratory en_US
dc.subject decompression en_US
dc.subject hydrogen en_US
dc.subject helium en_US
dc.subject nitrox en_US
dc.subject human en_US
dc.subject Forced vital capacity en_US
dc.subject forced expiratory volume in 1 second en_US
dc.subject maximal expiratory flow rate en_US
dc.subject maximal inspiratory flow rate en_US
dc.subject maximum voluntary ventilation en_US
dc.title [abstract] EFFECTS OF HYDROSTATIC PRESSURE ON ARTERIAL PCO2. en_US

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    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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