[abstract] THE MANDIBULAR OSTEORADIONECROSIS HBO TREATMENT; THE EXPERIENCE OF A HYPERBARIC OXYGEN CENTER THERAPY.

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[abstract] THE MANDIBULAR OSTEORADIONECROSIS HBO TREATMENT; THE EXPERIENCE OF A HYPERBARIC OXYGEN CENTER THERAPY.

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Title: [abstract] THE MANDIBULAR OSTEORADIONECROSIS HBO TREATMENT; THE EXPERIENCE OF A HYPERBARIC OXYGEN CENTER THERAPY.
Author: Pizzaballa, L; Maschio, M; Dosi, A; Salvoldi, T; Ferani, R; Marchesi, G
Abstract: BACKGROUND: Mandibular osteoradionecrosis is a side effect of Radiotherapic treatment of neoplastic oral tumours. The HBO also by it direct or indirect antibacterial effect is considered a treatment of such lesion. The Authors describe here their experience in the treatment of this pathology. METHODS: A retrospective study over 36 patients treated by radiotherapy for oral epithelial tumours (Tongue, tonsils, oral floor) and complicated by osteoradionecosis frequently (72.2 percent) associated with mucosal lesions is made. They are treated by HBO from 1987 to 1997 with HBO at 2.8 ATA (60 min of O2 breathing) or at 2.5 ATA (75 min of O2 breathing). The outcome of the treatment and the time needed to obtain a significant clinical result were studied. RESULTS: We studied 28 male and 8 female patients aged 32-79 years (mean 58.9). The 33 percent had bon exposition and in 4 cases the diagnosis of bacterial osteitis was done. The major symptoms referred by patients were pain (86.1 percent), trismus (36.1 percent), difficult swallowing (27.7 percent) and mastication (22.2 percent). 47.2 percent had cutaneous fistula draining saliva or pus. 48.9 +/- 34.6 Treatment were done (range 18-200). Complete recovery was seen in 9 patients (25 percent), 13 cases (36 percent) showed marked improvement of their pain, mastication and swallowing, and partial or complete recovery of mucosal lesion. 5 cases (13.8 percent) showed partial decrease of their symptoms and 8 (22.2 percent) were considered without improvement. 50 percent of cases with cutaneous fistula were closed about the end of treatment, and in the remaining 30 percent we assisted of initial signs of healing. The bon exposition of the alveolar process were covered by mucosa in 63.6 percent of the cases. CONCLUSIONS: The results of our study are encouraging. Nevertheless an extensive study with a standardised medical and surgical treatment in association with HBO is hardly requested.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org)
URI: http://archive.rubicon-foundation.org/4933
Date: 2000

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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