[abstract] GAS BUBBLES AND PLATELET AGGREGATION IN THE CEREBRAL VEINS DURING ACUTE DECOMPRESSION SICKNESS

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[abstract] GAS BUBBLES AND PLATELET AGGREGATION IN THE CEREBRAL VEINS DURING ACUTE DECOMPRESSION SICKNESS

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Title: [abstract] GAS BUBBLES AND PLATELET AGGREGATION IN THE CEREBRAL VEINS DURING ACUTE DECOMPRESSION SICKNESS
Author: Lehtosalo, J; Tervo, T; Laitinen, LA
Abstract: The brains of rats suffering from experimental decompression sickness (DCS) have been subjected to electron-microscopy for clarification of whether intravascular gas bubbles or other haematological alterations were present. The rats were exposed to 5,l bar air (134 ftm) for 90 min, and subsequently decompressed to the ambient pressure. After a decompression rate of 6,8 bar/min veins in the subarachnoideal space and superior sagittal sinuses always contained gas bubbles, no intravascular bubbles were found after a decompression rate of 1,5 bar/min. Under the electron microscope, platelet aggregates were observed at the electron-dense layer of the blood-bubble interface, as well as in pial veins with no bubbles. Platelets formed numerous pseudopods, and frequently appeared to be degranulated. Fibrin and multivesicular sacks were seen in the plasma. It is concluded that during DCS both activation and aggregation of platelets may occur in cerebral veins, even without bubbles. The high perfusion rate of the brain by blood might explain absence of the bubbles after 1,5 bar/min decompression rate, although this induced bubble formation in other body tissues.
Description: bstract of the Undersea and Hyperbaric Medical Society, Inc. Annual Scientific Meeting held May 25-29, 1981. The Asilomar Conference Center, Pacific Grove, California (http:www.uhms.org)
URI: http://archive.rubicon-foundation.org/4808
Date: 1981

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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