Skin allograft rejection and hyperbaric oxygen treatment in immune-histoincompatible mice

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Skin allograft rejection and hyperbaric oxygen treatment in immune-histoincompatible mice

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dc.contributor.author Erdmann, D en_US
dc.contributor.author Roth, AC en_US
dc.contributor.author Hussmann, J en_US
dc.contributor.author Lyons, SF en_US
dc.contributor.author Mody, NJ en_US
dc.contributor.author Kucan, JO en_US
dc.contributor.author Russell, RC en_US
dc.date.accessioned 2006-08-23T01:10:22Z
dc.date.available 2006-08-23T01:10:22Z
dc.date.issued 1995 en_US
dc.identifier.other Undersea Hyperb Med en_US
dc.identifier.uri PMID: 8574127 en_US
dc.identifier.uri http://archive.rubicon-foundation.org/2195
dc.description Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org ) en_US
dc.description.abstract The effect of hyperbaric oxygen (HBO) as an immunosuppressive agent was evaluated by using a highly immunogenic skin allograft mouse model. Immune-histoincompatible female C57BL/6 and BALB/c mice (N = 30) were randomly assigned to three groups receiving no treatment (control group), low dose HBO treatment (two treatments once a week), and intermediate HBO treatment (two treatments 3 times/wk) 1 wk before and 2 wk after transplantation of a 1.5 x 2 cm full thickness skin allograft from the back. Rejection was observed a Day 7 and was completed 14 days after surgery in controls. Low dose and intermediate HBO treatment delayed skin allograft rejection, which was histologically confirmed. en_US
dc.format.extent 700389 bytes
dc.format.mimetype application/pdf
dc.language.iso en_US
dc.rights Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org ) en_US
dc.source.uri null en_US
dc.subject HBO en_US
dc.subject hyperbaric en_US
dc.subject immunosuppressive en_US
dc.subject animal en_US
dc.subject mice en_US
dc.subject animal en_US
dc.subject mice en_US
dc.subject immune en_US
dc.subject.mesh Animals Female Graft Rejection/prevention & control* Hyperbaric Oxygenation* Immunocompetence Mice Mice, Inbred BALB C Mice, Inbred C57BL Random Allocation Surgical Flaps en_US
dc.title Skin allograft rejection and hyperbaric oxygen treatment in immune-histoincompatible mice en_US

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