[abstract] OXYGEN PREBREATHE IS AN EFFECTIVE NON-RECOMPRESSIVE STRATEGY FOR DISABLED SUBMARINE RESCUE

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[abstract] OXYGEN PREBREATHE IS AN EFFECTIVE NON-RECOMPRESSIVE STRATEGY FOR DISABLED SUBMARINE RESCUE

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Title: [abstract] OXYGEN PREBREATHE IS AN EFFECTIVE NON-RECOMPRESSIVE STRATEGY FOR DISABLED SUBMARINE RESCUE
Author: Soutiere, SE; Temple, DJ; Johnson, TO; Nelson, JW
Abstract: BACKGROUND: Disabled submarine (DISSUB) survivors are expected to achieve inert gas tissue saturation likely to cause severe decompression sickness (DCS). DISSUB rescue procedures cannot accommodate staged decompression and treatment chambers are limited. Alternatives to standard recompression for treating DCS are needed. Breathing 100percent O2 prior to decompression reduces the incidence of altitude DCS. Similarly, isobaric oxygen prebreathe can accelerate decompression in a DISSUB scenario. HYPOTHESIS: Isobaric oxygen breathing prior to rapid no-stop decompression from hyperbaric saturation will reduce the incidence of DCS and death. MATERIALS AND METHODS: Catheterized Yorkshire swine (72.8 +/- 5.9 kg) were placed into individual Plexiglas boxes within a hyperbaric chamber and compressed to 2.82 ATA for 22 h. Following saturation and while still at depth, gas to the boxes was remotely and independently switched. Animals received either 2 h air (control), 1 h air followed by 1 h 100percent oxygen (1hPB), or 2 h 100percent oxygen (2hPB). All boxes were then returned to air and the chamber was decompressed to 1ATA without stops (0.91 ATA min-1.) Dedicated observers recorded signs of DCS to the nearest minute for 2 h, then surviving animals were sacrificed. All animals underwent necropsy by a veterinary pathologist blinded to treatment. RESULTS: Oxygen prebreathe at 2.82 ATA eliminated death from saturation dropout. Type-II DCS was reduced from 85percent (11/13) in control animals to 8percent (1/13) with 1hPB, and 0percent (0/13) with 2hPB. Necropsy findings included significant decremental trends in cutis marmorata and ascites with increasing oxygen prebreathe. Incidence of pulmonary congestion was similar between treatment groups. Type-II DCS was highly correlated with the number (p less than 0.0001) and distribution (p less than 0.0001) of intravascular bubbles. CONCLUSIONS: The ability of oxygen prebreathe to eliminate death and reduce Type-II DCS after saturation warrants further study. Based on these results oxygen prebreathing could be expected to improve outcome in a DISSUB scenario.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: http://archive.rubicon-foundation.org/1722
Date: 2005

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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