[abstract] ONE YEAR FOLLOW-UP STUDY OF 1920 PATIENTS AFTER AN ACUTE CARBON MONOXIDE POISONING

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[abstract] ONE YEAR FOLLOW-UP STUDY OF 1920 PATIENTS AFTER AN ACUTE CARBON MONOXIDE POISONING

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Title: [abstract] ONE YEAR FOLLOW-UP STUDY OF 1920 PATIENTS AFTER AN ACUTE CARBON MONOXIDE POISONING
Author: Mathieu-Nolf, M; Mathieu, D; Durak-Carpeza, C; Linke, JC
Abstract: BACKGROUND: Carbon monoxide (CO) poisoning is well known to induce long term manifestations with severe consequences for the patient and high socio-economic cost. However, many discrepancies about the incidence and severity of these manifestations exist between studies mostly due to differences in time and evaluation method. We describe the long term clinical features after CO poisoning and evaluate their incidence. MATERIALS AND METHODS: One-year longitudinal prospective follow up study of all patients admitted to hospitals in our region for acute CO poisoning and alive at hospital discharge. Patients were treated by NBO2 or HBO2 following our protocol.1 Follow-up was done 1, 3, 6, and 12 months after discharge by the Lille Poison Centre. Information on patient clinical status was obtained by phone using a standardized questionnaire. The patient was considered to be symptomatic if any behavioural, neurological or other clinical symptoms had been observed by his physician or family and he had any complaints. RESULTS: A complete one-year follow-up was obtained for 1733 patients. At hospital discharge, 127 patients were symptomatic (7.3percent). Follow up shows a peak in patient complaints at 1 month 18.7percent. (324/1733), and a decrease thereafter 8.8percent at 3 months, 6.4percent at 6 months, 6.5percent at 1 year. At 1 year: seven patients have died but only 2 from a CO-related origin, one patient suffered from a gross neurological impairment, 22 (1.3percent) had memory impairment or behavioural changes. The other patients complain of mild subjective symptoms at home: headache, asthenia, and vertigo. All were returned to their previous occupation at least at 12 months. CONCLUSIONS: Follow-up after CO poisoning shows patient complaints peak at 1 month and decrease thereafter to plateau after 6 months. Following our proposal for oxygen therapy, long term manifestations of CO poisoning are of low frequency and induce only a mild degree of disability. 1Clinical Toxicology 1985; 3: 315-325.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: http://archive.rubicon-foundation.org/1686
Date: 2005

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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