[abstract] AN ONGOING STUDY INVESTIGATING THE LONGITUDINAL CHANGES IN QUALITY OF LIFE FOLLOWING HYPERBARIC OXYGEN THERAPY IN PATIENTS WITH MAXILLOFACIAL SOFT TISSUE- AND OSTEO-RADIONECROSIS

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[abstract] AN ONGOING STUDY INVESTIGATING THE LONGITUDINAL CHANGES IN QUALITY OF LIFE FOLLOWING HYPERBARIC OXYGEN THERAPY IN PATIENTS WITH MAXILLOFACIAL SOFT TISSUE- AND OSTEO-RADIONECROSIS

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Title: [abstract] AN ONGOING STUDY INVESTIGATING THE LONGITUDINAL CHANGES IN QUALITY OF LIFE FOLLOWING HYPERBARIC OXYGEN THERAPY IN PATIENTS WITH MAXILLOFACIAL SOFT TISSUE- AND OSTEO-RADIONECROSIS
Author: Harding, SA; Courtney, DJ; Hodder, SJ; Bryson, PJ
Abstract: Background. Long term prognosis for people with maxillofacial soft tissue- and osteo- radionecrosis is highly variable but, generally, there is a decline in functional status and high co-morbidity. Quality of life (QoL) changes have not been assessed in patients who have undergone hyperbaric oxygen therapy (HBO2). The authors have noted significant positive changes in QoL post-HBO2 in comparison with pre- HBO2 (unpublished data). The aims of this study are to observe the longer term changes in QoL, 6 and 12 months, after the completion of HBO2. Methods. From 2001 to 2004, patients referred for HBO2 following radiotherapy to head and neck cancers were asked to complete four questionnaires (pre, immediately post-HBO2, six, and twelve months post- HBO2). Scores between each time point were compared using Repeated Measures ANOVA with Tukey's post hoc analysis. Results. Currently 26 patients have completed the questionnaire at the 6 month time point (Mean age 58 years; male to female 3:1) and 12 patients at the 12 month time point (Mean age 60 years; male to female 5:8). The Medical Outcomes Short Form 36 showed patients' physical and emotional function improved (P=0.002) between post HBO2 to 6 months, and post HBO2 to 12 months, but mental health and vitality declined (P=0.02) between post HBO2 and 12 months. Changes were also identified on the EORTC H and N 35 module, with mouth opening ability increasing between pre HBO2 and 6 months post (P=0.025). Declines (P=0.039) were found in relation to sense of smell and taste. The declines identified in this study follow the same trend identified in maxillofacial patients not receiving HBO2. Conclusions. Patients undergoing HBO2 had long term changes in their QoL with respect to both psychological and functional status. This study is to be expanded with the introduction of a matched sample control group.
Description: Undersea and Hyperbaric Medical Society, Inc. (http://www.uhms.org )
URI: http://archive.rubicon-foundation.org/1504
Date: 2004

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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