[abstract]ADJUNCTIVE HYPERBARIC OXYGEN THERAPY FOR THE TREATMENT OF CHRONIC NON-HEALING ARTERIAL INSUFFICIENCY ULCERS

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[abstract]ADJUNCTIVE HYPERBARIC OXYGEN THERAPY FOR THE TREATMENT OF CHRONIC NON-HEALING ARTERIAL INSUFFICIENCY ULCERS

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Title: [abstract]ADJUNCTIVE HYPERBARIC OXYGEN THERAPY FOR THE TREATMENT OF CHRONIC NON-HEALING ARTERIAL INSUFFICIENCY ULCERS
Author: Iqbal, B; Heyboer, M; Byrne, J; Pons, P; McCaffrey, J; Wojcik, S; Morgan, M
Abstract: Introduction: Hyperbaric oxygen therapy (HBO2T) is used as an adjunctive treatment of select ischemic problem wounds. However, there is limited data regarding HBO2T’s effectiveness in the treatment of chronic non-healing arterial insufficiency ulcers (AIU) of the extremity. This study was designed to analyze healing rates and amputation rates in patients who underwent adjunctive HBO2T for a chronic non-healing AIU. Methods: A retrospective chart review was completed on 82 patients who underwent HBO2T from January 1, 2005 – December 31, 2011 for chronic non-healing arterial insufficiency ulcers of the extremity. Prior to HBO2T, patients were seen by a vascular surgeon and either underwent bypass/stent placement or were deemed ineligible for intervention. De-identified data was collected, including prior vascular interventions, co-morbidities, and documentation of complete healing and amputations. Results: The incidence of complete healing within 24 months of completion of HBO2T was 43.9 percent (36/82). The rate of major amputation was 17.1 percent (14/82). None of the patients who had healed required major amputation, whereas 42.4 percent (14/33) who were not healed within 24 months (p less than .0001) had a major amputation. The overall incidence of stent/bypass within one year prior to HBO2T was 36.6 percent (30/82). It was 30.6 percent (11/36) in those who healed and 39.4 percent (13/33) in those who did not heal. Conclusions: Our findings suggest adjunctive HBO2T can play a role in promotion of healing and limb salvage in chronic non-healing AIUs. The addition of adjunctive HBO2T resulted in a 44 percent healing rate in patients who had exhausted standard treatment and without an alternative were likely destined for major amputation. Although there is no control group, one would expect a failure rate nearing 100 percent in this patient population absent HBO2T. These results support the use of HBO2T for select chronic non-healing AIUs and the need for prospective studies.
Description: Undersea and Hyperbaric Medicine : Journal of the Undersea and Hyperbaric Medical Society, Inc.
URI: http://archive.rubicon-foundation.org/10483
Date: 2012

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  • UHMS Meeting Abstracts
    This is a collection of the published abstracts from the Undersea and Hyperbaric Medical Society (UHMS) annual meetings.

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